2-PROPANOL
MSDS Number: P6401 --- Effective Date: 01/24/02
1. Product Identification
Synonyms: Isopropyl alcohol; sec-propyl alcohol;
isopropanol; sec-propanol; dimethylcarbinol
CAS No.: 67-63-0
Molecular Weight: 60.10
Chemical Formula: (CH3)2 CHOH
Product Codes: 5373, 5582, 5806, 5863, 5870, 5873, 5890, 5996,
9016, 9025, 9026, 9059, 9078, 9079, 9081, 9082, 9083, 9084, 9088, 9089, 9095,
9334, XM-181
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------------ ---------
Isopropyl Alcohol 67-63-0 90 - 100% Yes
Water 7732-18-5 0 - 10% No
3. Hazards Identification
Emergency Overview
--------------------------
WARNING! FLAMMABLE LIQUID AND VAPOR. HARMFUL IF SWALLOWED OR INHALED.
CAUSES IRRITATION TO EYES AND RESPIRATORY TRACT. AFFECTS CENTRAL NERVOUS
SYSTEM. MAY BE HARMFUL IF ABSORBED THROUGH SKIN. MAY CAUSE IRRITATION TO
SKIN.
SAF-T-DATA(tm) Ratings (Provided here for
your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate
Flammability Rating: 3 - Severe
(Flammable)
Reactivity Rating: 2 - Moderate
Contact Rating: 3 - Severe
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT
HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red
(Flammable)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Inhalation:
Inhalation of vapors irritates the respiratory
tract. Exposure to high concentrations has a narcotic effect, producing
symptoms of dizziness, drowsiness, headache, staggering, unconsciousness and
possibly death.
Ingestion:
Can cause drowsiness,
unconsciousness, and death. Gastrointestinal pain, cramps, nausea, vomiting,
and diarrhea may also result. The single lethal dose for a human adult = about
250 mls (8 ounces).
Skin Contact:
May cause irritation with
redness and pain. May be absorbed through the skin with possible systemic
effects.
Eye Contact:
Vapors cause eye irritation. Splashes
cause severe irritation, possible corneal burns and eye damage.
Chronic
Exposure:
Chronic exposure may cause skin effects.
Aggravation
of Pre-existing Conditions:
Persons with pre-existing skin disorders
or impaired liver, kidney, or pulmonary function may be more susceptible to
the effects of this agent.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Call a
physician.
Ingestion:
Give large amounts of water to drink.
Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact:
Immediately flush skin with plenty of water for
at least 15 minutes. Call a physician if irritation develops.
Eye
Contact:
Immediately flush eyes with plenty of water for at least 15
minutes, lifting lower and upper eyelids occasionally. Get medical attention
immediately.
5. Fire Fighting Measures
Fire:
Flash point: 12C (54F) CC
Autoignition
temperature: 399C (750F)
Flammable limits in air % by volume:
lel: 2.0;
uel: 12.7
Listed fire data is for Pure Isopropyl Alcohol.
Explosion:
Above flash point, vapor-air mixtures are explosive
within flammable limits noted above. Contact with strong oxidizers may cause
fire or explosion. Vapors can flow along surfaces to distant ignition source
and flash back. Sensitive to static discharge.
Fire Extinguishing
Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide.
Water spray may be used to keep fire exposed containers cool, dilute spills to
nonflammable mixtures, protect personnel attempting to stop leak and disperse
vapors.
Special Information:
In the event of a fire, wear full
protective clothing and NIOSH-approved self-contained breathing apparatus with
full facepiece operated in the pressure demand or other positive pressure
mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition.
Wear appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from entering.
Contain and recover liquid when possible. Use non-sparking tools and
equipment. Collect liquid in an appropriate container or absorb with an inert
material (e. g., vermiculite, dry sand, earth), and place in a chemical waste
container. Do not use combustible materials, such as saw dust. Do not flush to
sewer! If a leak or spill has not ignited, use water spray to disperse the
vapors, to protect personnel attempting to stop leak, and to flush spills away
from exposures.
J. T. Baker SOLUSORB® solvent adsorbent is recommended
for spills of this product.
7. Handling and Storage
Protect against physical damage. Store in a cool, dry
well-ventilated location, away from any area where the fire hazard may be
acute. Outside or detached storage is preferred. Separate from incompatibles.
Containers should be bonded and grounded for transfers to avoid static sparks.
Storage and use areas should be No Smoking areas. Use non-sparking type tools
and equipment, including explosion proof ventilation. Containers of this
material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the product.
Small quantities of peroxides can form on prolonged storage. Exposure to light
and/or air significantly increases the rate of peroxide formation. If
evaporated to a residue, the mixture of peroxides and isopropanol may explode
when exposed to heat or shock.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
For Isopropyl Alcohol
(2-Propanol):
-OSHA Permissible Exposure Limit (PEL):
400 ppm
(TWA)
-ACGIH Threshold Limit Value (TLV):
400 ppm (TWA), 500 ppm
(STEL)
Ventilation System:
A system of local and/or general
exhaust is recommended to keep employee exposures below the Airborne Exposure
Limits. Local exhaust ventilation is generally preferred because it can
control the emissions of the contaminant at its source, preventing dispersion
of it into the general work area. Please refer to the ACGIH document,
Industrial Ventilation, A Manual of Recommended Practices, most recent
edition, for details.
Personal Respirators (NIOSH Approved):
If
the exposure limit is exceeded, a full facepiece respirator with organic vapor
cartridge may be worn up to 50 times the exposure limit or the maximum use
concentration specified by the appropriate regulatory agency or respirator
supplier, whichever is lowest. For emergencies or instances where the exposure
levels are not known, use a full-facepiece positive-pressure, air-supplied
respirator. WARNING: Air purifying respirators do not protect workers in
oxygen-deficient atmospheres.
Skin Protection:
Wear impervious
protective clothing, including boots, gloves, lab coat, apron or coveralls, as
appropriate, to prevent skin contact. Neoprene and nitrile rubber are
recommended materials.
Eye Protection:
Use chemical safety
goggles and/or a full face shield where splashing is possible. Maintain eye
wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Clear, colorless liquid.
Odor:
Rubbing alcohol.
Solubility:
Miscible in water.
Specific Gravity:
0.79 @ 20C/4C
pH:
No
information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
82C (180F)
Melting Point:
-89C
(-128F)
Vapor Density (Air=1):
2.1
Vapor Pressure (mm
Hg):
44 @ 25C (77F)
Evaporation Rate (BuAc=1):
2.83
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and
storage. Heat and sunlight can contribute to instability.
Hazardous
Decomposition Products:
Carbon dioxide and carbon monoxide may form
when heated to decomposition.
Hazardous Polymerization:
Will
not occur.
Incompatibilities:
Heat, flame, strong oxidizers,
acetaldehyde, acids, chlorine, ethylene oxide, hydrogen-palladium combination,
hydrogen peroxide-sulfuric acid combination, potassium tert-butoxide,
hypochlorous acid, isocyanates, nitroform, phosgene, aluminum, oleum and
perchloric acid.
Conditions to Avoid:
Heat, flames, ignition
sources and incompatibles.
11. Toxicological Information
Oral rat LD50: 5045 mg/kg; skin rabbit LD50: 12.8 gm/kg;
inhalation rat LC50: 16,000 ppm/8-hour; investigated as a tumorigen, mutagen,
reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Isopropyl Alcohol (67-63-0) No No 3
Water (7732-18-5) No No None
12. Ecological Information
Environmental Fate:
When released into the soil, this
material is expected to quickly evaporate. When released into the soil, this
material may leach into groundwater. When released into the soil, this
material may biodegrade to a moderate extent. When released to water, this
material is expected to quickly evaporate. When released into the water, this
material is expected to have a half-life between 1 and 10 days. When released
into water, this material may biodegrade to a moderate extent. This material
is not expected to significantly bioaccumulate. When released into the air,
this material is expected to be readily degraded by reaction with
photochemically produced hydroxyl radicals. When released into the air, this
material is expected to have a half-life between 1 and 10 days. When released
into the air, this material may be removed from the atmosphere to a moderate
extent by wet deposition.
Environmental Toxicity:
The
LC50/96-hour values for fish are over 100 mg/l. This material is not expected
to be toxic to aquatic life.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be
handled as hazardous waste and sent to a RCRA approved incinerator or disposed
in a RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations. Dispose of container
and unused contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: ISOPROPANOL
Hazard Class: 3
UN/NA: UN1219
Packing Group: II
Information reported for
product/size: 355LB
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: ISOPROPANOL
Hazard Class: 3
UN/NA: UN1219
Packing Group: II
Information reported for product/size: 355LB
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Isopropyl Alcohol (67-63-0) Yes Yes Yes Yes
Water (7732-18-5) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Isopropyl Alcohol (67-63-0) Yes Yes No Yes
Water (7732-18-5) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Isopropyl Alcohol (67-63-0) No No Yes No
Water (7732-18-5) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Isopropyl Alcohol (67-63-0) No No No
Water (7732-18-5) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Mixture / Liquid)
Australian Hazchem Code: 2[S]2
Poison
Schedule: None allocated.
WHMIS:
This MSDS has been
prepared according to the hazard criteria of the Controlled Products
Regulations (CPR) and the MSDS contains all of the information required by the
CPR.
16. Other Information
NFPA Ratings: Health: 2 Flammability: 3
Reactivity: 0
Label Hazard Warning:
WARNING! FLAMMABLE
LIQUID AND VAPOR. HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO EYES
AND RESPIRATORY TRACT. AFFECTS CENTRAL NERVOUS SYSTEM. MAY BE HARMFUL IF
ABSORBED THROUGH SKIN. MAY CAUSE IRRITATION TO SKIN.
Label
Precautions:
Keep away from heat, sparks and flame.
Keep container
closed.
Use only with adequate ventilation.
Wash thoroughly after
handling.
Avoid breathing vapor or mist.
Avoid contact with eyes, skin
and clothing.
Label First Aid:
If swallowed, give large amounts
of water to drink. Never give anything by mouth to an unconscious person. If
inhaled, remove to fresh air. If not breathing, give artificial respiration.
If breathing is difficult, give oxygen. In case of contact, immediately flush
eyes or skin with plenty of water for at least 15 minutes. Remove contaminated
clothing and shoes. Wash clothing before reuse. In all cases, get medical
attention.
Product Use:
Laboratory Reagent.
Revision
Information:
MSDS Section(s) changed since last revision of document
include: 3.
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************
Prepared by: Environmental Health & Safety
Phone Number:
(314) 654-1600 (U.S.A.)