IODINE TINCTURE 2%
MSDS Number: I2682 --- Effective Date: 09/27/99
1. Product Identification
Synonyms: Ethyl alcohol solution
CAS No.: Not
applicable to mixtures.
Molecular Weight: Not applicable to
mixtures.
Chemical Formula:
Product Codes: 2214
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Ethyl Alcohol 64-17-5 40 - 55% Yes
Iodine 7553-56-2 1 - 5% Yes
Sodium Iodide 7681-82-5 1 - 5% Yes
Water 7732-18-5 35 - 58% No
3. Hazards Identification
Emergency Overview
--------------------------
POISON! DANGER! FLAMMABLE LIQUID AND VAPOR. MAY BE FATAL IF SWALLOWED
OR INHALED. CAUSES SEVERE IRRITATION OR BURNS TO EVERY AREA OF CONTACT.
AFFECTS CENTRAL NERVOUS SYSTEM, BLOOD, LIVER, REPRODUCTIVE SYSTEM AND
CARDIOVASCULAR SYSTEM. VAPORS CAUSE SEVERE IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT. MAY CAUSE ALLERGIC SKIN OR RESPIRATORY REACTION.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for
your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 1 - Slight
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 0 - None
Contact Rating: 1 - Slight
Lab
Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B
EXTINGUISHER
Storage Color Code: Red (Flammable)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Iodine Component: The following hazards are for concentrated
solutions. Hazards of less concentrated solutions should be reduced.
Inhalation:
Ethyl Alcohol Component:
Vapors may irritate
mucous membranes of upper respiratory tract. Prolonged exposure to high air
concentration of ethyl alcohol may produce drowsiness, loss of appetite, and
intoxication.
Iodine Component:
Vapors severely irritate and can
burn the mucous membranes and respiratory tract. Excessive tears, rhinitis,
tightness in the chest, sore throat, headache and delayed pulmonary edema can
result. Inhalation of concentrated vapors may be fatal.
Ingestion:
Ethyl Alcohol Component:
Large oral doses may produce burning sensation
in mouth and esophagus as well as gastrointestinal disturbances, sleep
disorders, and central nervous system effects.
Iodine
Component:
Can cause severe burns of the mouth, throat and stomach. Causes
abdominal pain, diarrhea, fever, vomiting, stupor and shock. Probable lethal
dose is 2 to 4 gm of free iodine.
Skin Contact:
Ethyl Alcohol
Component: May cause skin discoloration with irritation. Irritating due to
defatting action on skin. Causes redness, pain, drying and cracking of the
skin. Iodine Component: Contact may cause blistering burns, irritation, and
pain. Vapors may be severely irritating to the skin.
Eye Contact:
Ethyl Alcohol Component: Vapors can cause irritation. Splashes can cause
severe irritation and possibly eye damage. Iodine Component: Vapors are
severely irritating and may cause damage to the eyes. Contact may cause severe
burns and permanent eye damage.
Chronic Exposure:
Ethyl Alcohol
Component:
Prolonged contact may cause skin discoloration. May cause drying
cracking, and dermatitis. Ethanol may cause reproductive effects such as birth
defects, developmental problems and may damage the reproductive system.
Repeated high exposure may damage the liver, nervous system and blood cells.
Iodine Component:
Chronic exposure to iodine may cause insomnia,
conjunctivitis, inflammation of the nasal mucous, bronchitis, tremor, rapid
heart beat, diarrhea and weight loss. Allergic sensitization may occur.
Chronic iodine overdoses have produced iodism. Headache, fever, sneezing,
salivation, and skin rashes may occur.
Aggravation of Pre-existing
Conditions:
Persons with pre-existing skin disorders, eye problems,
impaired respiratory function, or disease of the thyroid, lungs, or kidney may
be more susceptible to the effects of the substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Get medical
attention immediately. Observe for the development of pulmonary edema.
Ingestion:
Induce vomiting immediately as directed by medical
personnel. Never give anything by mouth to an unconscious person. Get medical
attention immediately.
Skin Contact:
Wipe off excess material
from skin then immediately flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Get medical attention
immediately. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Iodine stains can be removed by immediately washing skin with 5% sodium
thiosulfate solution.
Eye Contact:
Immediately flush eyes with
plenty of water for at least 15 minutes, lifting lower and upper eyelids
occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire:
Flash point: 22C (72F) CC
Autoignition
temperature: 363C (685F)
Flammable limits in air % by volume:
lel: 3.3;
uel: 19
Flammable Liquid and Vapor! Flash point is applicable for 60%
ethanol. All other fire data is for pure ethanol.
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable
limits noted above. Sensitive to static discharge.
Fire Extinguishing
Media:
Dry chemical, alcohol foam or carbon dioxide. Water may be
ineffective. Use water spray to cool fire-exposed containers, to dilute
liquid, and control vapor.
Special Information:
In the event of
a fire, wear full protective clothing and NIOSH-approved self-contained
breathing apparatus with full facepiece operated in the pressure demand or
other positive pressure mode. Water may be used to flush spills away from
exposures and to dilute spills to non-flammable mixtures.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition.
Wear appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from entering.
Contain and recover liquid when possible. Use non-sparking tools and
equipment. Collect liquid in an appropriate container or absorb with an inert
material (e. g., vermiculite, dry sand, earth), and place in a chemical waste
container. Do not use combustible materials, such as saw dust. Do not flush to
sewer!
J. T. Baker SOLUSORB(R) solvent adsorbent is recommended for
spills of this product.
7. Handling and Storage
Protect against physical damage. Store in a cool, dry
well-ventilated location, away from any area where the fire hazard may be
acute. Outside or detached storage is preferred. Separate from incompatibles.
Containers should be bonded and grounded for transfers to avoid static sparks.
Storage and use areas should be No Smoking areas. Use non-sparking type tools
and equipment, including explosion proof ventilation. Containers of this
material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
Iodine Component:
-OSHA
Permissible Exposure Limit (PEL):
0.1 ppm Ceiling
-ACGIH Threshold Limit
Value (TLV):
0.1 ppm (STEL) ceiling
For Ethyl Alcohol:
- OSHA
Permissible Exposure Limit (PEL):
1,000 ppm (TWA)
- ACGIH Threshold
Limit Value (TLV):
1,000 ppm (TWA), A4 (Not Classifiable as a Human
Carcinogen)
Ventilation System:
A system of local and/or
general exhaust is recommended to keep employee exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because it
can control the emissions of the contaminant at its source, preventing
dispersion of it into the general work area. Please refer to the ACGIH
document, Industrial Ventilation, A Manual of Recommended Practices,
most recent edition, for details. Use explosion-proof equipment.
Personal Respirators (NIOSH Approved):
If the exposure limit is
exceeded, wear a supplied air, full-facepiece respirator, airlined hood, or
full-facepiece self-contained breathing apparatus. This substance has poor
warning properties.
Skin Protection:
Wear impervious protective
clothing, including boots, gloves, lab coat, apron or coveralls, as
appropriate, to prevent skin contact.
Eye Protection:
Use
chemical safety goggles and/or a full face shield where splashing is possible.
Maintain eye wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Clear, reddish brown liquid.
Odor:
Characteristic iodine odor.
Solubility:
Miscible in water.
Specific Gravity:
0.95 - 1.0
pH:
No information found.
% Volatiles by volume @ 21C
(70F):
> 90 (as water and alcohol)
Boiling Point:
No
information found.
Melting Point:
No information found.
Vapor Density (Air=1):
No information found.
Vapor
Pressure (mm Hg):
No information found.
Evaporation Rate
(BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and
storage.
Hazardous Decomposition Products:
Carbon dioxide and
carbon monoxide may form when heated to decomposition. Burning may produce
toxic iodine vapors.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Ethyl Alcohol Component:
Strong oxidizing
agents and many other substances.
Iodine Component:
Ammonia, strong
acids, powdered metals, alkali metals, acetaldehyde, acetylene, ammonium
hydroxide, and strong reducing agents.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Toxicological Data:
Sodium iodide: Oral rat LD50: 4340
mg/kg Irritation skin rabbit, Standard Draize: 500 mg/24H, moderate; Eye
rabbit, Standard Draize: 100 mg/24H, investigated as a reproductive
effector.
Ethyl Alcohol: Oral rat LD50: 7060 mg/kg; Inhalation rat
LC50: 20,000 ppm/10-hour; Irritation skin rabbit, Standard Draize: 20 mg/24H,
moderate; eye rabbit, Standard Draize: 500 mg/24H severe; Investigated as a
tumorigen, mutagen, and a reproductive effector.
Iodine
Component:
Oral rat LD50: 14 gm/kg; Human LDLo: 28 mg/kg; Investigated as a
reproductive effector.
Reproductive Toxicity:
Ethanol has been
linked to birth defects in humans. Occasional uses of iodides for asthma in
pregnancy has resulted in fetal death, severe goiter, and cretinoid appearance
of the newborn.
Carcinogenicity:
Ethanol has been linked to
cancer in humans. Chronic ethanol ingestion is associated with liver cancer.
Most industrial ethanol contains denaturants that render it undesirable to
drink.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Ethyl Alcohol (64-17-5) No No None
Iodine (7553-56-2) No No None
Sodium Iodide (7681-82-5) No No None
Water (7732-18-5) No No None
12. Ecological Information
Environmental Fate:
The following statements refer to
the environmental fate of ethanol. When released into the soil, this material
is expected to readily biodegrade. When released into the soil, this material
may leach into groundwater. When released into the soil, this material is
expected to quickly evaporate. When released into water, this material is
expected to readily biodegrade. When released into water, this material may
evaporate to a moderate extent. This material is not expected to significantly
bioaccumulate. When released into the air, this material is expected to be
readily degraded by reaction with photochemically produced hydroxyl radicals.
When released into the air, this material is expected to be readily removed
from the atmosphere by wet deposition.
The following statements refer
to the environmental fate of iodine. This material has a log octanol-water
partition coefficient of less than 3.0. This material is not expected to
significantly bioaccumulate.
Environmental Toxicity:
The
following information refers to the toxicity of ethanol. This material is not
expected to be toxic to aquatic life. The LC50/96-hour values for fish are
over 100 mg/l.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be
handled as hazardous waste and sent to a RCRA approved incinerator or disposed
in a RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations. Dispose of container
and unused contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: ETHANOL SOLUTION
Hazard Class: 3
UN/NA: UN1170
Packing Group: II
Information reported for
product/size: 500ML
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: ETHANOL
SOLUTION
Hazard Class: 3.2
UN/NA: UN1170
Packing
Group: II
Information reported for product/size: 500ML
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: ETHANOL SOLUTION
Hazard Class: 3
UN/NA: UN1170
Packing Group: II
Information reported for
product/size: 500ML
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Ethyl Alcohol (64-17-5) Yes Yes Yes Yes
Iodine (7553-56-2) Yes Yes No Yes
Sodium Iodide (7681-82-5) Yes Yes Yes Yes
Water (7732-18-5) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Ethyl Alcohol (64-17-5) Yes Yes No Yes
Iodine (7553-56-2) Yes Yes No Yes
Sodium Iodide (7681-82-5) Yes Yes No Yes
Water (7732-18-5) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Ethyl Alcohol (64-17-5) No No No No
Iodine (7553-56-2) No No No No
Sodium Iodide (7681-82-5) No No No No
Water (7732-18-5) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Ethyl Alcohol (64-17-5) No No No
Iodine (7553-56-2) No No No
Sodium Iodide (7681-82-5) No No No
Water (7732-18-5) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Mixture / Liquid)
Australian Hazchem Code: 2[S]E
Poison
Schedule: S6
WHMIS:
This MSDS has been prepared according
to the hazard criteria of the Controlled Products Regulations (CPR) and the
MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 2 Flammability: 3
Reactivity: 0
Label Hazard Warning:
POISON! DANGER!
FLAMMABLE LIQUID AND VAPOR. MAY BE FATAL IF SWALLOWED OR INHALED. CAUSES
SEVERE IRRITATION OR BURNS TO EVERY AREA OF CONTACT. AFFECTS CENTRAL NERVOUS
SYSTEM, BLOOD, LIVER, REPRODUCTIVE SYSTEM AND CARDIOVASCULAR SYSTEM. VAPORS
CAUSE SEVERE IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. MAY CAUSE
ALLERGIC SKIN OR RESPIRATORY REACTION.
Label Precautions:
Keep
away from heat, sparks and flame.
Use only with adequate ventilation.
Do
not breathe vapor or mist.
Keep container closed.
Do not get in eyes, on
skin, or on clothing.
Wash thoroughly after handling.
Label First
Aid:
If swallowed, induce vomiting immediately as directed by medical
personnel. Never give anything by mouth to an unconscious person. If inhaled,
remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact, wipe off excess
material from skin then immediately flush eyes or skin with plenty of water
for at least 15 minutes while removing contaminated clothing and shoes. Wash
clothing before reuse. In all cases get medical attention immediately.
Product Use:
Laboratory Reagent.
Revision
Information:
MSDS Section(s) changed since last revision of document
include: 5.
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************
Prepared by: Strategic Services Division
Phone Number: (314)
539-1600 (U.S.A.)