BIORAD Wash Reagent 1957115
MSDS Number: B2310 --- Effective Date: 09/20/97
1. Product Identification
Synonyms: Methanol; Methyl alcohol
CAS No.:
67-56-1
Molecular Weight: 32.04
Chemical Formula: CH3OH
Product Codes: 5849, 5877
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Methyl Alcohol 67-56-1 90 - 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
POISON! DANGER! VAPOR HARMFUL. MAY BE FATAL OR CAUSE BLINDNESS IF
SWALLOWED. HARMFUL IF INHALED OR ABSORBED THROUGH SKIN. CANNOT BE MADE
NONPOISONOUS. FLAMMABLE LIQUID AND VAPOR. CAUSES IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT. AFFECTS THE CENTRAL NERVOUS SYSTEM, GASTROINTESTINAL TRACT
AND LIVER.
J.T. Baker SAF-T-DATA(tm) Ratings
(Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 3 - Severe (Poison)
Flammability Rating: 3 - Severe
(Flammable)
Reactivity Rating: 1 - Slight
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT
HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red
(Flammable)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Inhalation:
A slight irritant to the mucous membranes.
Toxic effects exerted upon nervous system, particularly the optic nerve. Once
absorbed into the body, it is very slowly eliminated. Symptoms of overexposure
may include headache, drowsiness, nausea, vomiting, blurred vision, blindness,
coma, and death. A person may get better but then worse again up to 30 hours
later.
Ingestion:
Toxic. Symptoms parallel inhalation. Can
intoxicate and cause blindness. Usual fatal dose: 100-125 milliliters.
Skin Contact:
Methyl alcohol is a defatting agent and may cause
skin to become dry and cracked. Skin absorption can occur; symptoms may
parallel inhalation exposure.
Eye Contact:
Irritant. Continued
exposure may cause eye lesions.
Chronic Exposure:
Marked
impairment of vision and enlargement of the liver has been reported. Repeated
or prolonged exposure may cause skin irritation.
Aggravation of
Pre-existing Conditions:
Persons with pre-existing skin disorders or
eye problems or impaired liver or kidney function may be more susceptible to
the effects of the substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Get medical
attention immediately.
Ingestion:
Induce vomiting immediately
as directed by medical personnel. Never give anything by mouth to an
unconscious person. Get medical attention immediately.
Skin
Contact:
Immediately flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Get medical attention
immediately. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at
least 15 minutes, lifting lower and upper eyelids occasionally. Get medical
attention immediately.
5. Fire Fighting Measures
Fire:
Flash point: 11C (52F) CC
Autoignition
temperature: 464C (867F)
Flammable limits in air % by volume:
lel: 6.0;
uel: 36.0
Flammable Liquid and Vapor!
Explosion:
Moderate
explosion hazard and dangerous fire hazard when exposed to heat, sparks or
flames. Vapors can flow along surfaces to distant ignition source and flash
back. Above flash point, vapor-air mixtures are explosive within flammable
limits noted above. Sealed containers may rupture when heated. Sensitive to
static discharge.
Fire Extinguishing Media:
Water spray, dry
chemical, alcohol foam, or carbon dioxide.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode. Use water spray to blanket
fire, cool fire exposed containers, and to flush non-ignited spills or vapors
away from fire.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition.
Wear appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from entering.
Contain and recover liquid when possible. Use non-sparking tools and
equipment. Collect liquid in an appropriate container or absorb with an inert
material (e. g., vermiculite, dry sand, earth), and place in a chemical waste
container. Do not use combustible materials, such as saw dust. Do not flush to
sewer! If a leak or spill has not ignited, use water spray to disperse the
vapors, to protect personnel attempting to stop leak, and to flush spills away
from exposures. US Regulations (CERCLA) require reporting spills and releases
to soil, water and air in excess of reportable quantities. The toll free
number for the US Coast Guard National Response Center is (800) 424-8802.
J. T. Baker SOLUSORB(tm) solvent adsorbent is recommended for spills
of this product.
7. Handling and Storage
Protect against physical damage. Store in a cool, dry
well-ventilated location, away from any area where the fire hazard may be
acute. Outside or detached storage is preferred. Separate from incompatibles.
Containers should be bonded and grounded for transfers to avoid static sparks.
Storage and use areas should be No Smoking areas. Use non-sparking type tools
and equipment, including explosion proof ventilation. Containers of this
material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the product.
Do Not attempt to clean empty containers since residue is difficult to remove.
Do not pressurize, cut, weld, braze, solder, drill, grind or expose such
containers to heat, sparks, flame, static electricity or other sources of
ignition: they may explode and cause injury or death.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
For Methyl Alcohol:
- OSHA
Permissible Exposure Limit (PEL):
200 ppm (TWA)
- ACGIH Threshold Limit
Value (TLV):
200 ppm (TWA), 250 ppm (STEL) skin
Ventilation
System:
A system of local and/or general exhaust is recommended to
keep employee exposures below the Airborne Exposure Limits. Local exhaust
ventilation is generally preferred because it can control the emissions of the
contaminant at its source, preventing dispersion of it into the general work
area. Please refer to the ACGIH document, Industrial Ventilation, A Manual
of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is
exceeded, wear a supplied air, full-facepiece respirator, airlined hood, or
full-facepiece self-contained breathing apparatus.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat,
apron or coveralls, as appropriate, to prevent skin contact.
Eye
Protection:
Use chemical safety goggles and/or a full face shield
where splashing is possible. Maintain eye wash fountain and quick-drench
facilities in work area.
9. Physical and Chemical Properties
Appearance:
Clear, colorless liquid.
Odor:
Pungent odor.
Solubility:
Complete (100%)
Specific
Gravity:
0.7915 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling
Point:
64.7C (149F)
Melting Point:
- 97.8C (-144F)
Vapor Density (Air=1):
1.11
Vapor Pressure (mm Hg):
127 @ 25C (77F)
Evaporation Rate (BuAc=1):
4.6
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and
storage.
Hazardous Decomposition Products:
May form carbon
dioxide, carbon monoxide, and formaldehyde when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizing agents such as nitrates,
perchlorates or sulfuric acid. Will attack some forms of plastics, rubber, and
coatings. May react with metallic aluminum and generate hydrogen gas.
Conditions to Avoid:
Heat, flames, ignition sources and
incompatibles.
11. Toxicological Information
Methyl Alcohol (Methanol): LD50 oral rat 5628 mg/kg; LC50
inhalation rat 64000 ppm/4H; LD50 skin rabbit 15800 mg/kg; Irritation
data-standard Draize test: skin, rabbit 20mg/24hr, moderate; eye, rabbit 100
mg/24 hr, moderate; Investigated as a mutagen and reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Methyl Alcohol (67-56-1) No No None
12. Ecological Information
Environmental Fate:
When released into the soil, this
material is expected to readily biodegrade. When released into the soil, this
material is expected to leach into groundwater. When released into the soil,
this material is expected to quickly evaporate. When released into the water,
this material is expected to have a half-life between 1 and 10 days. When
released into water, this material is expected to readily biodegrade. When
released into the air, this material is expected to exist in the aerosol phase
with a short half-life. When released into the air, this material is expected
to be readily degraded by reaction with photochemically produced hydroxyl
radicals. When released into air, this material is expected to have a
half-life between 10 and 30 days. When released into the air, this material is
expected to be readily removed from the atmosphere by wet deposition.
Environmental Toxicity:
This material is expected to be
slightly toxic to aquatic life.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be
handled as hazardous waste and sent to a RCRA approved incinerator or disposed
in a RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations. Dispose of container
and unused contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: METHANOL
Hazard Class: 3
UN/NA: UN1230
Packing Group: II
Information reported for
product/size: 940ML
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: METHANOL
Hazard Class: 3.2, 6.1
UN/NA: UN1230
Packing Group:
II
Information reported for product/size: 940ML
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: METHANOL
Hazard Class: 3.2, 6.1
UN/NA: UN1230
Packing Group: II
Information reported for
product/size: 940ML
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Methyl Alcohol (67-56-1) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Methyl Alcohol (67-56-1) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Methyl Alcohol (67-56-1) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Methyl Alcohol (67-56-1) 5000 U154 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
Australian Hazchem Code: 2PE
Poison
Schedule: S6
WHMIS:
This MSDS has been prepared according
to the hazard criteria of the Controlled Products Regulations (CPR) and the
MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 1 Flammability: 3
Reactivity: 0
Label Hazard Warning:
POISON! DANGER!
VAPOR HARMFUL. MAY BE FATAL OR CAUSE BLINDNESS IF SWALLOWED. HARMFUL IF
INHALED OR ABSORBED THROUGH SKIN. CANNOT BE MADE NONPOISONOUS. FLAMMABLE
LIQUID AND VAPOR. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
AFFECTS THE CENTRAL NERVOUS SYSTEM, GASTROINTESTINAL TRACT AND LIVER.
Label Precautions:
Avoid breathing vapor.
Keep container
closed.
Use only with adequate ventilation.
Wash thoroughly after
handling.
Avoid contact with eyes, skin and clothing.
Keep away from
heat, sparks and flame.
Label First Aid:
If inhaled, remove to
fresh air. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. If swallowed, induce vomiting immediately as directed
by medical personnel. Never give anything by mouth to an unconscious person.
In case of contact, immediately flush eyes or skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes. Wash clothing
before reuse. In all cases get medical attention immediately.
Product
Use:
Laboratory Reagent.
Revision Information:
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************
Prepared by: Strategic Services Division
Phone Number: (314)
539-1600 (U.S.A.)